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Anti-Influenza A, HA (Clone: Flu-5J8)

Anti-Influenza A, HA (Clone: Flu-5J8) (LT579-GRP)

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Description

Hemagglutinin (HA) is a glycoprotein on the Influenza A (IAV) viral surface1. HA consists of two domains: an antigenically variable head and a more conserved stem. There are 18 HA subtypes. Neutralizing antibodies targeting the head domain are typically restricted to within subtype, while antibodies targeting the stem offer broader protection. In contrast, Flu-5J8 targets the HA globular head and offers broad protection2. Flu-5J8 inhibits all 1918 to 1977 H1N1 strains tested plus the pandemic 2009 strain but not the seasonal H1N1 strains from 1999 or 2007.

Specifications

Manufacturer Leinco Technologies Inc
Manufacturer Cat# LT579
Concentration ≥1.0 mg/ml
Formulation This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Clone Flu-5J8
Target Influenza A Hemagglutinin
Applications ELISA, FC, N
Antigen HA is on the viral surface.
Storage Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one year. For longer term storage, aseptically aliquot in working volumes without diluting and store at ≥ -70°C. Avoid Repeated Freeze Thaw Cycles.
Protein Flu A, HA