Anti-Human/Mouse Integrin β7 - Purified <i>In vivo </i>PLATINUM™ Functional Grade
Anti-Human/Mouse Integrin β7 - Purified <i>In vivo </i>PLATINUM™ Functional Grade (F2196-GRP)
Products
Description
Integrin β7 is a 130 kD highly flexible membrane protein in the Ig superfamily that plays a role in lymphocyte adhesion. This flexibility facilitates a dynamic affinity for ligand via conformational changes. Integrin β7 forms heterodimers with α4 or αE (ITGAE) for structural stability. The α4/β7 heterodimer, also known as LPAM-1, binds to VCAM-1, MAdCAM-1 and fibronectin. The αE/β7 heterodimer interacts with E-Cadherin. Integrin β7 interacts with EED.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | F2196 |
| Concentration | ≥ 2.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium, calcium or preservatives added. |
| Isotype | IgG2a κ |
| Clone | FIB27 |
| Applications | B, FC |
| Protein | Integrin Beta 7 |