Anti-Human VE-Cadherin (Clone 123433)
Anti-Human VE-Cadherin (Clone 123433) (V148-GRP)
Products
Description
Vascular endothelial-cadherin (VE-Cadherin) also known as cadherin-5 is an endothelial specific, homophilic adhesion molecule located at the lateral cell surface.1 VE-Cadherin is crucial for the proper assembly of vascular structures and the maintenance of vascular integrity.2 It plays a pivotal role in the formation, maturation and remodeling of the vascular wall.3 VE-cadherin is a positive and endothelial cell-specific regulator of transforming growth factor-beta (TGF-beta) signaling. Therefore, the reduction or inactivation of VE-cadherin may contribute to progression of diseases where TGF-beta signaling is impaired.4
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | V148 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Vascular Endothelial Cadherin Cadherin-5 (CDH5) 7B4 CD144 VE-Cad VEC 123433 VE-Cadherin Human Anti-Human VE-Cadherin |
| Isotype | IgG1 |
| Clone | 123433 |
| Target | VE-Cadherin |
| Antibody Type | Monoclonal |
| Applications | ELISA Indirect, WB |
| Storage | -20°C to -70°C |
| Protein | VE-Cadherin |