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Anti-Human TROP-2 (Clone 77220)

Anti-Human TROP-2 (Clone 77220) (T454-GRP)

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Description

Trop-2 is a cell surface glycoprotein1 that is highly expressed in a wide variety of epithelial cancers. There is little or no expression of Trop-2 in adult somatic tissue.2 Trop-2 is a novel calcium signal transducer3 involved in the regulation of cell- cell adhesion.4 It is an oncogene that has potential as a therapeutic target.2 It is a possible candidate gene for diagnosis and molecular target therapy of colorectal cancer.5

Specifications

Manufacturer Leinco Technologies Inc
Manufacturer Cat# T454
Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Alternate Names Monoclonal Antibody TROP-2 Tumor-Associated Calcium Signal Transducer 2 (TACSTD2) EGP-1 GA733 GA733-1 M1S1 T16 GP50 77220 Human Anti-Human TROP-2
Isotype IgG2a
Clone 77220
Target TROP-2
Antibody Type Monoclonal
Applications CyTOF®, FC, WB
Storage -20°C to -70°C
Protein TROP-2