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Anti-Human TRAIL R2

Anti-Human TRAIL R2 (T451-GRP)

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Description

Tumor necrosis factor-related apoptosis-inducing ligand Receptor 2 (TRAIL-R2) is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling.1 The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells.2 TRAIL-R2 has been shown to be associated with a decrease in the survival rates of breast cancer patients.3

Specifications

Manufacturer Leinco Technologies Inc
Manufacturer Cat# T451
Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Alternate Names Monoclonal Antibody TNF-Related Apoptosis-Inducing Ligand Receptor 2 TNFRSF10B CD262 DR5 KILLER TRICK2 TRICK2A TRICK2B TRICKB ZTNFR9 71903 TRAIL R2 Human Anti-Human TRAIL R2
Isotype IgG1
Clone 71903
Target TRAIL R2
Antibody Type Monoclonal
Applications ELISA Indirect, FA, WB
Storage -20°C to -70°C
Protein TRAIL R2