Anti-Human TCR Vα24-Jα18 (iNKT cell)- APC
£272.81
Anti-Human TCR Vα24-Jα18 (iNKT cell)- APC (T1708-100ug)
Product
| Cat # T1708-100ug | Size 100 µg |
Price
£272.81
|
Qty
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Description
TCR Vα24-Jα18 antibody, 6B11, recognizes the CDR3 region of the V alpha 24 and J alpha 18 TCR alpha locus (Vα24-Jα18). The Vα24-Jα18 semi-invariant TCR is expressed on a highly conserved T cell subset, named invariant natural killer T (iNKT cells), which also express NK cell-associated molecules. The Vα24-Jα18 TCR recognizes lipid antigens, such as α-galactosylceramide (α-GalCer), presented by the MHC class I-like molecule CD1d1. Following activation, iNKT cells rapidly proliferate and produce large amounts of IL-4, IFNγ, and cytolytic mediators2,3. iNKT cells have both inflammatory and immunoregulatory functions and are implicated in anti-tumor immunity, protection against infections, suppression of autoimmunity, and the development of inflammatory diseases4.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | T1708 |
| Product Size | 100 µg |
| Concentration | 0.2 mg/ml |
| Formulation | This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Clone | 6B11 |
| Target | TCR Vα24-Jα18 |
| Applications | FC |
| Antigen | The Vα24-Jα18 TCR is expressed on iNKT cells. |
| Storage | This Allophycocyanin (APC) conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | TCR Vα24-Jα18 |