Anti-Human T Cell Cytokine Receptor (CT) (TCCR)
Anti-Human T Cell Cytokine Receptor (CT) (TCCR) (T209-GRP)
Products
Description
Upon antigen challenge, T-helper cells differentiate into two functional distinct subsets, Th1 and Th2. Th1 cells produce IL-2, IFN-γ and lymphotoxin-β that augment cell mediated immune response while Th2 cells secrete IL-4, IL-5, and IL-10 that enhance humoral immunity. The function of T-helper cells is regulated by cytokines. A novel cytokine receptor was recently identified and cloned.1,2 It is a new member in the type I cytokine receptor family and designated TCCR for T-cell cytokine receptor and WSX-1.1,2 TCCR deficient mice had impaired Th1 responses to protein antigen challenge, including decreased levels of IFN-γ and Th1-dependent antibody IgG2a. TCCR is predominately expressed in thymus, spleen, lymph nodes and peripheral blood leukocytes.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | T209 |
| Concentration | 0.5 mg/ml |
| Formulation | This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. |
| Target | T Cell Cytokine Receptor |
| Antibody Type | Polyclonal |
| Applications | IHC FFPE, WB |
| Storage | This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Protein | T Cell Cytokine Receptor |