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Anti-Human PDGF Rβ (Clone 61520)

Anti-Human PDGF Rβ (Clone 61520) (P278-GRP)

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Description

Platelet-derived growth factor receptor-β (PDGFRβ) is a well-characterized plasma membrane receptor with endogeneous tyrosine kinase activity, which is autophosphorylated in response to binding of dimeric platelet-derived growth factor (PDGF) ligand.1 PDGFRβ mediates signaling important for the proliferation, migration, and survival of mesenchymal cells.2 PDGFRβ is found in all cell types 3 and is activated in breast carcinoma cells and indicate a possible role of the receptor in breast cancerogenesis.4

Specifications

Manufacturer Leinco Technologies Inc
Manufacturer Cat# P278
Formulation This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present.
Alternate Names Monoclonal Antibody Platelet-Derived Growth Factor Receptor Beta TEL PDGFRB FLJ12858 PDGF2 SIS SSV C-sis CD140B JTK12 PDGFR PDGFR1 61520 PDGF Rβ Human Anti-Human PDGF Rβ
Isotype IgG1
Clone 61520
Target PDGF R beta
Antibody Type Monoclonal
Applications WB
Storage -20°C to -70°C
Protein PDGF R beta