Anti-Human Oncostatin M (Clone 17001)
Anti-Human Oncostatin M (Clone 17001) (O126-GRP)
Products
Description
Oncostatin M (OSM) is a pleitropic cytokine produced by activated T lymphocytes and monocytes that is structurally and functionally related to the subfamily of cytokines known as the IL-6-type cytokine family.1 OSM either inhibits or enhances the growth of cells depending on cell type. It inhibits proliferation of skeletal muscle cells by blocking cell cycle progression from G(1) to S phase.2 OSM is also a key mediator for proliferation and anti-apoptosis of hepatocytes which suggests that OSM gene therapy is useful, as preventive and curative means, for the treatment of patients with liver damage.3
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | O126 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Oncostatin M 17001 OSM Human Anti-Human Oncostatin M |
| Isotype | IgG2a |
| Clone | 17001 |
| Target | Oncostatin M |
| Antibody Type | Monoclonal |
| Applications | ELISA Cap, N, WB |
| Storage | -20°C to -70°C |
| Protein | Oncostatin M |