Anti-Human NT-3 (Clone41512)
Anti-Human NT-3 (Clone41512) (N200-GRP)
Products
Description
Neurotrophin 3 (NT-3), also known as NTF3 is a basic protein found in neurons of the central nervous system. NT-3 selectively supports the survival of neuronal cell populations. It rapidly potentiate the spontaneous and impulse-evoked synaptic activity of developing neuromuscular synapses in culture and thus appears to be involved in the regulation of functions of developing synapses.1,2,3 NT-3 negatively modulates nerve growth factor (NGF) receptor expression and associated nociceptive phenotype in intact neurons, suggesting a beneficial role in treating aspects of neuropathic pain mediated by NGF. NT-3 is effective at suppressing thermal hyperalgesia associated with chronic constriction injury (CCI).4
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | N200 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Neurotrophin-3 Nerve Growth Factor-2 (NGF-2) HGN NTF3 HDNF MGC129711 41512 NT-3 Human Anti-Human NT-3 |
| Isotype | IgG1 |
| Clone | 41512 |
| Target | NT-3 |
| Antibody Type | Monoclonal |
| Applications | ELISA Cap, N |
| Storage | -20°C to -70°C |
| Protein | NT-3 |