Anti-Human Neuregulin 1-β1 (NRG1-β1) - Biotin
£543.75
Anti-Human Neuregulin 1-β1 (NRG1-β1) - Biotin (N212-50ug)
Product
| Cat # N212-50ug | Size 50 µg |
Price
£543.75
|
Qty
|
Description
Neuregulin/Heregulin is a family of related growth factors that are differentially spliced variants of four genes: NRG1, NRG2, NRG3 and NRG4. The longest forms of NRG contains several different modular domains and tissue-specific splicing results in many NRG isoforms containing different sets of these domains. Alternative splicing produces two types of EGF domain, designated a and b. HRG-Beta1 contains an Ig domain and an EGF domain necessary for direct binding to receptor tyrosine kinases erbB-3 and erbB-4. HRG-Beta1 binding causes erbB-3 and erbB-4 to dimerize with erbB-2 (Her2/neu) and thereby regulates the phosphorylation of erbB-2 tyrosines. HRG-Beta1 stimulates proliferation and motility of breast cancer cells and plays a role in wound healing by stimulating epidermal migration and differentiation of epidermal cells and by stimulating the expression of integrins in the epidermis.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | N212 |
| Product Size | 50 µg |
| Alternate Names | Neuregulin 1-b b beta1 Neuregulin 1b b beta1 Neuregulin 1 b b beta1 Anti-Human NRG1-b b beta1Biotin Antigen Aff. Pur. NRG1-b b beta1 NRG1b b beta1 NRG1 b b beta1 Anti-Human NRG1-b b beta1Biotin Antigen Aff. Pur. HRG1-b b beta1 HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor HRG1b b beta1 HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor HRG1 b b beta1 HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor Anti-Human NRG1-b b beta1Biotin Antigen Aff. Pur. Polyclonal Antibody Neuregulin 1-b b beta1 HRG1-b b beta1 HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor NRG1-b b beta1 Human Anti-Human NRG1-b b beta1/HRG1-b b beta1 EGF domain-BiotinAntigen Aff. Pur. Polyclonal Antibody Neuregulin 1b b beta1 HRG1b b beta1 HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor NRG1b b beta1 Human AntiHuman NRG1b b beta1/HRG1b b beta1 EGF domainBiotinAntigen Aff. Pur. Polyclonal Antibody Neuregulin 1 b b beta1 HRG1 b b beta1 HRG Breast Cancer Cell Differentiation Factor p45 Acetylcholine Receptor Inducing Activity ARIA Glial Factor Neu Differentiation Factor NRG1 b b beta1 Human Anti Human NRG1 b b beta1/HRG1 b b beta1 EGF domain BiotinAntigen Aff. Pur. Anti-Human NRG1-b b beta1Biotin Antigen Aff. Pur. |
| Target | NRG1-β1 |
| Antibody Type | Polyclonal |
| Applications | WB |
| Storage | -20°C to -70°C |