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Anti-Human MMP-2

Anti-Human MMP-2 (M1300-GRP)

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Description

Matrix metallopeptidase 2, also known as MMP2, is an enzyme involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. MMP-2 degrades type IV collagen, the major structural component of basement membranes and plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. MMP2 has been found to be associated with tumor invasion in various cancers.1

Specifications

Manufacturer Leinco Technologies Inc
Manufacturer Cat# M1300
Formulation This recombinant protein was lyophilized from a 0.2 μm filtered solution in 30% acetonitrile (CH3CN) and 0.1% trifluoroacetic acid (TFA).
Alternate Names Polyclonal Antibody MMP-2 CLG4 CLG4A MMP-II MONA TBE-1 MMP-2 Human MMP-2 Anti-Human MMP-2
Target MMP-2
Antibody Type Polyclonal
Applications IHC, IP
Storage -20°C to -70°C
Protein MIP-4