Anti-Human MIP-1β (Clone 24006)
Anti-Human MIP-1β (Clone 24006) (M1270-GRP)
Products
Description
Both MIP-1 alpha and MIP-1 beta are structurally and functionally related CC chemokines. They participate in the host response to invading bacterial, viral, parasite and fungal pathogens by regulating the trafficking and activation state of selected subgroups of inflammatory cells e.g. macrophages, lymphocytes and NK cells. While both MIP-1 alpha and MIP-1 beta exert similar effects on monocytes their effect on lymphocytes differ; with MIP-1 alpha selectively attracting CD8+ lymphocytes and MIP-1 beta selectively attracting CD4+ lymphocytes. Additionally, MIP-1 alpha and MIP-1 beta have also been shown to be potent chemoattractants for B cells, eosinophils and dendritic cells.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | M1270 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody MIP-1β CCL4 ACT2 AT744.1 G-26 LAG1 MGC104418 MGC126025 MGC126026 MIP1B1 SCYA2 SCYA4 24006 MIP-1β Human Anti-Human MIP-1β |
| Isotype | IgG2b |
| Clone | 24006 |
| Target | MIP-1 beta |
| Antibody Type | Monoclonal |
| Applications | CyTOF®, ELISA Cap, FC, N, WB |
| Storage | -20°C to -70°C |
| Protein | MIP-1 beta |