Anti-Human LIGHT (Clone 115520)
Anti-Human LIGHT (Clone 115520) (L219-GRP)
Products
Description
LIGHT is a type II transmemebrane protein and a member of the TNF cytokine family also referred to as TNFSF14 and it is identical with HVEM ligand. LIGHT is expressed in splenocytes, activated PBL, CD8+ tumor infiltrating lymphocytes, granulocytes and monocytes. LIGHT has the ability to activate NFkB, stimulate proliferation of lymphocytes, and induce apoptosis in certain human tumor cells. LIGHT binds to three receptors; the herpes virus entry mediator type A receptor (HEVM), LTbR and a decoy receptor (DcR3).1
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | L219 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody LIGHT TNFSF14 HVEM-L TR2 CD258 LTg 115520 Human Anti-Human LIGHT |
| Isotype | IgG1 |
| Clone | 115520 |
| Target | LIGHT |
| Antibody Type | Monoclonal |
| Applications | CyTOF®, ELISA Cap, FC |
| Storage | -20°C to -70°C |
| Protein | LIGHT |