Anti-Human Leptin (Clone 44802)
Anti-Human Leptin (Clone 44802) (L109-GRP)
Products
Description
Leptin is a neuroendocrine hormone secreted from adipose tissue that plays a key role in regulating energy intake and energy expenditure, including appetite and metabolism. Leptin is one of the most important adipose derived hormones.1 It interacts with six types of receptors and once it binds to OB-Receptor it activates the stat3, which is phosphorylated and travels to the nucleus to effect changes in gene expression. One of the main effects on gene expression is the down-regulation of the expression of endocannabinoids.2 High leptin levels are associated with psoriasis.3
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | L109 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Leptin Obesity Protein (OB) B219 LEP OBS 44802 Human Anti-Human Leptin |
| Isotype | IgG1 |
| Clone | 44802 |
| Target | Leptin |
| Antibody Type | Monoclonal |
| Applications | ELISA Cap, N |
| Storage | -20°C to -70°C |
| Protein | Leptin |