Anti-Human IL-4 [Clone 3010]
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Anti-Human IL-4 [Clone 3010] (I-173-500ug)
Product
Description
IL-4 is a 15-19 kD pleiotropic immune cytokine secreted by activated TH2 cells. It has many biological roles, including the regulation in humoral and adaptive immunity, the inhibition of bone resorption, the stimulation of activated B-cell and T-cell proliferation, and initiation of allergic responses. Moreover, IL-4 induces a positive feedback loop by stimulating differentiation of naive helper T cells, or Th0 cells, to Th2 cells which in turn secrete more IL-4. Increased IL-4 production and overproduction of IL-4R are found in many cancers. IL-4 has a significant effect on tumor progression by increasing apoptosis resistance via tumor growth enhancement. IL-4 may also play a part in the immune dysregulation that occurs in most HIV-1 infected patients.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-173 |
| Product Size | 500 µg |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Interleukin-4 BCGF BCDF B Cell Stimulating Factor BSF-1 3010 IL-4 Human Anti-Human IL-4 |
| Isotype | IgG1 |
| Clone | 3010 |
| Target | IL-4 |
| Antibody Type | Monoclonal |
| Applications | ELISA Cap, WB |
| Storage | -20°C to -70°C |
| Protein | IL-4 |