Anti-Human IL-4 Allophycocyanin (APC) (Clone: MP4-25D2)
Anti-Human IL-4 Allophycocyanin (APC) (Clone: MP4-25D2) (I-1166-GRP)
Products
Description
IL-4 is a 15-19 kD pleiotropic immune cytokine secreted by activated TH2 cells. It has many biological roles, including the regulation in humoral and adaptive immunity, the inhibition of bone resorption, the stimulation of activated B-cell and T-cell proliferation, and initiation of allergic responses. Moreover, IL-4 induces a positive feedback loop by stimulating differentiation of naive helper T cells, or Th0 cells, to Th2 cells which in turn secrete more IL-4. Increased IL-4 production and overproduction of IL-4R are found in many cancers. IL-4 has a significant effect on tumor progression by increasing apoptosis resistance via tumor growth enhancement. IL-4 may also play a part in the immune dysregulation that occurs in most HIV-1 infected patients.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-1166 |
| Concentration | 0.1 mg/ml |
| Formulation | This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (PBS) pH 7.4, 150 mM NaCl, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody Interleukin-4 BCGF BCDF B Cell Stimulating Factor BSF-1 MP4-25D2 IL-4 Human Anti-Human IL-4 - APC |
| Isotype | IgG1 |
| Clone | MP4-25D2 |
| Antibody Type | Monoclonal |
| Applications | FC |
| Storage | 2-8°C |
| Protein | IL-4 |