Anti-Human IL-2R alpha (CD25) (Basiliximab) - Fc Muted™Anti-Human IL-2R alpha (CD25) (Basiliximab) - Fc Muted™
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Anti-Human IL-2R alpha (CD25) (Basiliximab) - Fc Muted™

CD25, a 55 kD type I transmembrane glycoprotein, has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Many resting memory T cells constitutively express IL2Rα. It functions as the receptor for HTLV-1, resulting in its expression on neoplastic cells in adult T cell lymphoma/leukemia. CD25 (sIL-2R) has been used to track disease progression. Some additional clinical applications include Chagas disease, a disease characterized by a decline of CD25 expression on immune cells, and Multiple sclerosis, in which treatments with mAbs target CD25. Anti-Human IL-2R alpha (CD25) (Basiliximab) utilizes the same variable regions from the therapeutic antibody Basiliximab making it ideal for research projects.
Cat# Size Price Qty Buy
LT305-1mg 1.0 mg
£1,312.50
LT305-0.2mg 0.2 mg
£328.13
LT305-25ug 25 ug
£107.81

Additional Information

Property Value or Rating
Manufacturer Cat# LT305
Concentration ≥ 2.0 mg/ml
Formulation This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium, calcium or preservatives added.
Manufacturer Leinco Technologies Inc
Isotype IgG1 κ
Clone Hu107
Applications B, CyTOF®, FC, IF, IHC, WB
Antigen IL-2Rα is expressed on activated mature T and B lymphocytes, during early stages of thymocytes development, pre-B cells, and in activated CD4+ memory T-lymphocytes.
Storage Functional grade biosimilar antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Protein CD25

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