Anti-Human IL-2R alpha (CD25) (Basiliximab) - APC
£203.44
Anti-Human IL-2R alpha (CD25) (Basiliximab) - APC (LT303-50ug)
Product
| Cat # LT303-50ug | Size 50 µg |
Price
£203.44
|
Qty
|
Description
CD25, a 55 kD type I transmembrane glycoprotein, has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Many resting memory T cells constitutively express IL2Rα. It functions as the receptor for HTLV-1, resulting in its expression on neoplastic cells in adult T cell lymphoma/leukemia. CD25 (sIL-2R) has been used to track disease progression. Some additional clinical applications include Chagas disease, a disease characterized by a decline of CD25 expression on immune cells, and Multiple sclerosis, in which treatments with mAbs target CD25. Anti-Human IL-2R alpha (CD25) (Basiliximab) utilizes the same variable regions from the therapeutic antibody Basiliximab making it ideal for research projects.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | LT303 |
| Product Size | 50 µg |
| Concentration | 0.2 mg/ml |
| Formulation | This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Clone | Hu107 |
| Target | CD25 |
| Applications | FC, IF, IHC |
| Antigen | IL-2Rα is expressed on activated mature T and B lymphocytes, during early stages of thymocytes development, pre-B cells, and in activated CD4+ memory T-lymphocytes. |
| Storage | This Allophycocyanin (APC) conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | CD25 |