Anti-Human IL-13 Rα2 (Clone 83834)
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Anti-Human IL-13 Rα2 (Clone 83834) (I-688-500ug)
Product
Description
Interleukin 13 receptor alpha 2, also known as IL13RA2 and CD213A2, binds IL13 with high affinity, but lacks cytoplasmic domain, and does not appear to function as a signal mediator. IL13RA2 serves as a dominant negative inhibitor or a decoy receptor for IL-13.1 IL-13Ralpha2 is a promising target for ovarian cancer therapy, and the soluble form of IL-13R may be a possible surrogate marker for disease monitoring.2 IL13RA2 signaling during prolonged inflammation is also an important therapeutic target for the prevention of TGF-beta(1)-mediated fibrosis.3
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-688 |
| Product Size | 500 µg |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Interleukin-13 Receptor Alpha 2 IL13RA2 CD213A2 IL-13R IL13BP 83834 IL-13 Rα2 Human Anti-Human IL-13 Rα2 |
| Isotype | IgG1 |
| Clone | 83834 |
| Target | IL-13 R alpha 2 |
| Antibody Type | Monoclonal |
| Applications | WB |
| Storage | -20°C to -70°C |
| Protein | IL-13 R alpha 2 |