Anti-Human IL-10 Rα
£0.00
Anti-Human IL-10 Rα (I-644-500ug)
Product
Description
Interleukin 10 receptor, alpha subunit is a subunit for the interleukin-10 receptor. IL10RA has also recently been designated CDW210A (cluster of differentiation W210A). It is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-644 |
| Product Size | 500 µg |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Interleukin-10 Receptor Alpha IL10RA CDW210A HIL-10R IL-10R1 IL10R CD210 37607 IL-10 Rα Human Anti-Human IL-10 Rα |
| Isotype | IgG1 |
| Clone | 37607 |
| Target | IL-10 R alpha |
| Antibody Type | Monoclonal |
| Applications | N |
| Storage | -20°C to -70°C |
| Protein | IL-10 R alpha |