Anti-Human IL-1 RII (Clone 34117)
Anti-Human IL-1 RII (Clone 34117) (I-641-GRP)
Products
Description
Interleukin 1 receptor type II (IL1R2), also known as CD121b (Cluster of Differentiation 121b), is a transmembrane protein found on B lymphocytes, neutrophils, monocytes, large granular leukocytes and endothelial cells. It is a decoy receptor known for its ability to buffer IL-1 effects.1 IL-1RII is involved in the control of the proinflammatory state that takes place in the endometrium during the premenstrual and menstrual periods.2 IL-1RII can neutralize IL-1 beta and counteract its effect on endometrial stromal cells, and may provide a new clinical strategy for the treatment of endometriosis.3
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-641 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Interleukin-1 Soluble Receptor Type II IL1R2 CD121b IL1RB MGC47725 34117 IL-1 sRII Human Anti-Human IL-1 RII |
| Isotype | IgG1 |
| Clone | 34117 |
| Antibody Type | Monoclonal |
| Applications | ELISA Indirect, WB |
| Storage | -20°C to -70°C |
| Protein | IL-1 sRII |