Anti-Human IGFBP-1 (Clone 33627)
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Anti-Human IGFBP-1 (Clone 33627) (I-695-500ug)
Product
Description
Insulin-like growth factor binding protein 1, also known as IGFBP1, is a member of the insulin-like growth factor binding protein (IGFBP) family that are cysteine-rich proteins that act as a carrier protein. The protein binds both insulin-like growth factors (IGFs) I and II and circulates in the plasma. Binding of this protein prolongs the half-life of the IGFs and alters their interaction with cell surface receptors. IGFBP-1 is particularly important in female reproductive physiology, where it is involved with other factors in a complex system which regulates menstrual cycles, puberty, ovulation, decidualization, implantation and fetal growth. There is evidence for a pathophysiological role for IGFBP-1 in pre-eclampsia, intrauterine growth restriction, polycystic ovarian syndrome and trophoblast and endometrial neoplasms.1
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-695 |
| Product Size | 500 µg |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Insulin-Like Growth Factor Binding Protein 1 IBP-1 Placenta Protein 12 (PP12) AFBP IGF-BP25 HIGFBP-1 33627 IGFBP-1 Human Anti-Human IGFBP-1 |
| Isotype | IgG1 |
| Clone | 33627 |
| Target | IGFBP-1 |
| Antibody Type | Monoclonal |
| Applications | ELISA Cap, N, WB |
| Storage | -20°C to -70°C |
| Protein | IGFBP-1 |