Anti-Human IFN-γ Rα Chain (CD119)
Anti-Human IFN-γ Rα Chain (CD119) (I-691-GRP)
Products
Description
IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-691 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Interferon Gamma Receptor 1 CD119 IFN-γR IFN-γRα IFN-α R1 CDw119 92101 IFN-γ R1 Human Anti-Human IFN-γ R1 |
| Isotype | IgG1 |
| Clone | 92101 |
| Antibody Type | Monoclonal |
| Applications | ELISA Indirect, FC, N, WB |
| Antigen | The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes. |
| Storage | -20°C to -70°C |
| Protein | IFNγ Rα |