Anti-Human ICAM-3 (Clone 76205)
£581.25
Anti-Human ICAM-3 (Clone 76205) (I-713-500ug)
Product
| Cat # I-713-500ug | Size 500 µg |
Price
£581.25
|
Qty
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Description
Intercellular adhesion molecule 3 (ICAM3) also known as CD50 (Cluster of Differentiation 50) is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins that bind to the leukocyte adhesion LFA-1 protein. This protein is constitutively and abundantly expressed by all leucocytes and may be the most important ligand for LFA-1 in the initiation of the immune response. It functions not only as an adhesion molecule, but also as a potent signaling molecule. ICAM-3 is potentially the most important ligand for LFA-1 in the initiation of the immune response because the expression of ICAM-1 on resting leukocytes is low.1 ICAM-3 is closely related to ICAM-1. 1 ICAM-3 is essentially restricted to the haemopoietic system and is reciprocal in its expression to ICAM-1, in that it is present on resting cells and its level falls as a result of cell activation.2
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-713 |
| Product Size | 500 µg |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Intercellular Adhesion Molecule 3 CD50 CDW50 ICAM-R 76205 ICAM-3 Human Anti-Human ICAM-3 |
| Isotype | IgG1 |
| Clone | 76205 |
| Target | ICAM-3 |
| Antibody Type | Monoclonal |
| Applications | B, WB |
| Storage | -20°C to -70°C |
| Protein | ICAM-3 |