Anti-Human I-Kappa-B Kinase Epsilon (CT) (IKKε)
£89.06
Anti-Human I-Kappa-B Kinase Epsilon (CT) (IKKε) (I-303-20ug)
Product
| Cat # I-303-20ug | Size 20 µg |
Price
£89.06
|
Qty
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Description
Nuclear factor kappa B (NF-κB) is a ubiquitous transcription factor and an essential mediator of gene expression during activation of immune and inflammatory responses. NF-κB mediates the expression of a great variety of genes in response to extracellular stimuli. NF-κB is associated with IkB proteins in the cell cytoplasm, which inhibit NF-κB activity. IkB is phosphorylated by IkB kinase (IKK) complex that contains IKKα, IKKβ, and IKKγ. A novel molecule in the IKK complex was recently identified and designated IKKε/IKK-i.1,2 IKKe is required for the activation of NF-κB by PMA and T cell receptors but not by TNFα and IL-1.1 IKKε/IKK-i message is supexpressed in a variety of tissues and is inducible by TNFα, IL-1, and LPS.2
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | I-303 |
| Product Size | 20 µg |
| Concentration | 0.5 mg/ml |
| Formulation | This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. |
| Target | I-Kappa-B Kinase Epsilon |
| Applications | IHC FFPE, WB |
| Storage | This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Protein | I-Kappa-B Kinase Epsilon |