Anti-Human gp130 (Clone 28126)
Anti-Human gp130 (Clone 28126) (G666-GRP)
Products
Description
Glycoprotein 130 (also known as gp130, IL6ST, IL6-beta or CD130) is a transmembrane protein which is the founding member of the class of tall cytokine receptors. It forms one subunit of type I cytokine receptors within the IL-6 receptor family. It is often referred to as the common gp130 subunit, and is important for signal transduction following cytokine engagement.1 Gp130 signals are mediated by tyrosine kinases of the JAK family and by their binding partners, transcription factors of the STAT family.2 Gp130 signaling is very important for osteoblast function and calcium homeostasis.3
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | G666 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Glycoprotein 130 IL6ST IL6β CD130 CDw130 GP130 GP130-RAPS IL6R-Beta 28126 gp130 Human Anti-Human gp130 |
| Isotype | IgG1 |
| Clone | 28126 |
| Target | gp130 |
| Antibody Type | Monoclonal |
| Applications | CyTOF®, FC, N |
| Storage | -20°C to -70°C |
| Protein | gp130 |