Anti-Human GITR (Clone 110416)
Anti-Human GITR (Clone 110416) (G678-GRP)
Products
Description
GITR (glucocorticoid-induced tumor necrosis factor receptor) also known as TNFRSF18, is a surface receptor molecule that has been shown to be involved in inhibiting the suppressive activity of T-regulatory cells and extending the survival of T-effector cells.1 GITR is involved in the regulation of T-cell receptor mediated cell death. Constitutive expression of a transfected GITR gene induces resistance to apoptosis induced by anti CD3 monoclonal antibodies. GITR ligand interferes with the suppressor activity of CD4(+) CD25(+) regulatory T-cells.2
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | G678 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Glucocorticoid Induced Tumor Necrosis Factor Receptor TNFRSF18 AITR GITR-D 110416 GITR Human Anti-Human GITR |
| Isotype | IgG1 |
| Clone | 110416 |
| Target | GITR |
| Antibody Type | Monoclonal |
| Applications | ELISA Cap, FC, N, WB |
| Storage | -20°C to -70°C |
| Protein | GITR |