Anti-Human GFRα-3
Anti-Human GFRα-3 (G677-GRP)
Products
Description
GDNF family receptor alpha 3, also known as GFRA3 is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor and a member of the GDNF receptor family. It forms a signaling receptor complex with RET tyrosine kinase receptor and binds the ligand, artemin. GFRalpha3 preferentially binds the newest member of the glial-derived neurotrophic factor family of ligands, artemin. The major site of GFRalpha3 expression is in the dorsal root ganglion. GFRalpha3 artemin neurons are immunopositive for markers expected of nociceptors and include a subset of neurons distinct from the GDNF-responsive population.1
Specifications
| Manufacturer Cat# | G677 |
|---|---|
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Glial Cell Line-Derived Neurotropic Factor Receptor Alpha 3 GDNFRγ GDNFR Gamma 111004 GFRα-3 Human Anti-Human GFRα-3 |
| Isotype | IgG1 |
| Clone | 111004 |
| Target | GDNF R alpha-3 |
| Antibody Type | Monoclonal |
| Applications | WB |
| Storage | -20°C to -70°C |
| Protein | GDNF R alpha-3 |