Anti-Human Flt-3 Ligand
Anti-Human Flt-3 Ligand (F108-GRP)
Products
Description
Fms-related tyrosine kinase 3 ligand (FLT3LG) is a hematopoietic four helical bundle cytokine. It is structurally homologous to stem cell factor (SCF) and colony stimulating factor 1 (CSF-1). In synergy with other growth factors, such as IL-7 and IL-3, Flt-3 ligand promotes long-term expansion and differentiation of human pro-B-cells.1,2 Flt3 ligand is a cytokine capable of inducing large numbers of dendritic cells that dramatically enhances the sensitivity of antigen-specific B and T cell responses to systemic injection of a soluble protein. Through a CD40-CD40 ligand-dependent mechanism Flt-3 Ligand influences the class of antibody produced and enables productive immune responses.3
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | F108 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Polyclonal Antibody Flt3-Ligand Fms-Related Tyrosine Kinase 3 Ligand Flk-2 Ligand FL FLT3LG STK-1 Ligand Human Flt-3 Ligand Anti-Human Flt-3 Ligand |
| Isotype | IgG2a |
| Clone | 133706 |
| Target | FLT3LG |
| Antibody Type | Polyclonal |
| Applications | N, WB |
| Storage | -20°C to -70°C |
| Protein | FGF R2 |