Anti-Human CNTF (Clone 21809)
Anti-Human CNTF (Clone 21809) (C1387-GRP)
Products
Description
Ciliary neurotrophic factor (CNTF) is a cytokine that supports survival and/or differentiation of a variety of neuronal cell types including sensory, sympathetic, and motoneurons.1,2 With these abilities, CNTF has implications for Parkinson's disease and cell-replacement therapies for other disorders.3 CNTF mimics the biological actions of leptin while overcoming "leptin resistance" and appears to reduce inflammatory signaling cascades associated with lipid accumulation in liver and skeletal muscle. The advantages and disadvantages of CNTF has shown promise as a therapeutic strategy to alleviate obesity-associated diseases.4
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C1387 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Isotype | IgG2a |
| Clone | 21809 |
| Target | CNTF |
| Antibody Type | Monoclonal |
| Applications | ELISA Indirect, N, WB |
| Protein | CNTF |