Anti-Human CD86- PE
Anti-Human CD86- PE (C1537-GRP)
Products
Description
CD86 is an 80kD Ig superfamily member that is involved in immunoglobulin class-switching and activation of NK cell-mediated cytotoxicity. CD80 is closely related to, and works in tandem with CD86 to prime T- cells. CD86 is expressed earlier in the immune response than CD80. The ligation of CD28 on T cells with CD80 and CD86 on APCs co-stimulates T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD86 can also bind to CTLA-4 to deliver an inhibitory signal to T cells.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | C1537 |
| Formulation | This monoclonal antibody is conjugated to R-phycoerythrin (R-PE) and formulated in modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 0.1% sodium azide as a preservative. |
| Isotype | IgG1 |
| Clone | 37301 |
| Target | CD86 |
| Applications | FC |
| Antigen | CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. |
| Storage | This R-phycoerythrin (R-PE) conjugate is stable for at least twelve months when stored at 2-8°C protected from light. Do not freeze. |
| Protein | CD86 |