Anti-Human CD86 (B7-2) [Clone 37301]
Anti-Human CD86 (B7-2) [Clone 37301] (B567-GRP)
Products
Description
CD86 is an 80kD Ig superfamily member that is involved in immunoglobulin class-switching and activation of NK cell-mediated cytotoxicity. CD80 is closely related to, and works in tandem with CD86 to prime T- cells. CD86 is expressed earlier in the immune response than CD80. The ligation of CD28 on T cells with CD80 and CD86 on APCs co-stimulates T cells resulting in enhanced cell activation, proliferation, and cytokine production. CD86 can also bind to CTLA-4 to deliver an inhibitory signal to T cells.
Specifications
| Manufacturer | Leinco Technologies Inc |
|---|---|
| Manufacturer Cat# | B567 |
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody B7-2 CD86 37301 Human Anti-Human B7-2 |
| Isotype | IgG1 |
| Clone | 37301 |
| Target | CD86 |
| Antibody Type | Monoclonal |
| Applications | CyTOF®, FC, N, WB |
| Antigen | CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. |
| Storage | -20°C to -70°C |
| Protein | CD86 |