Anti-Human CD62L - Purified (PhenoCyler-Fusion (CODEX)® Ready)
£89.06
Anti-Human CD62L - Purified (PhenoCyler-Fusion (CODEX)® Ready) (C512-50ug)
Product
| Cat # C512-50ug | Size 50 µg |
Price
£89.06
|
Qty
|
Description
CD62L antibody, clone DREG56, recognizes CD62L, also known as L-selectin or LECAM-1, a 74-95 kDa type I transmembrane glycoprotein and cell adhesion molecule expressed on most circulating leukocytes1. Ligands for CD62L include CD34, GlyCAM-1, and MAdCAM-1, which require sialyation, fucosylation, and carbohydrate sulfation for recognition2,3. Ligand binding mediates tethering and rolling of leukocytes, facilitating entry into secondary lymphoid organs, including lymph nodes and Peyer’s patches, via high endothelial venules (HEVs)1. CD62L is also expressed on human embryo trophoblasts and has been proposed to play a role in human embryo implantation4.
Specifications
| Manufacturer Cat# | C512 |
|---|---|
| Product Size | 50 µg |
| Concentration | 0.5 mg/ml |
| Formulation | This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4. |
| Clone | DREG56 |
| Target | CD62L |
| Applications | IHC FF, PhenoCycler® |
| Antigen | CD62L is expressed on most circulating leukocytes, including neutrophils, monocytes, T, B and NK cells, and human embryo trophoblasts. |
| Storage | This antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CD62L |