Anti-Human CD62L - APC
Anti-Human CD62L - APC (C2273-GRP)
Products
Description
CD62L antibody, clone DREG56, recognizes CD62L, also known as L-selectin or LECAM-1, a 74-95 kDa type I transmembrane glycoprotein and cell adhesion molecule expressed on most circulating leukocytes1. Ligands for CD62L include CD34, GlyCAM-1, and MAdCAM-1, which require sialyation, fucosylation, and carbohydrate sulfation for recognition2,3. Ligand binding mediates tethering and rolling of leukocytes, facilitating entry into secondary lymphoid organs, including lymph nodes and Peyer’s patches, via high endothelial venules (HEVs)1. CD62L is also expressed on human embryo trophoblasts and has been proposed to play a role in human embryo implantation4.
Specifications
| Manufacturer Cat# | C2273 |
|---|---|
| Concentration | 0.2 mg/ml |
| Formulation | This Allophycocyanin (APC) conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Alternate Names | Monoclonal Antibody L-Selectin Mel-14 LAM-1 LEU-8 DREG56 CD62L Human Anti-Human CD62L (L-Selectin) - APC |
| Isotype | IgG1 |
| Clone | DREG56 |
| Target | CD62L |
| Antibody Type | Monoclonal |
| Applications | FC |
| Antigen | CD62L is expressed on most circulating leukocytes, including neutrophils, monocytes, T, B and NK cells, and human embryo trophoblasts. |
| Storage | This APC conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | CD62L |