Anti-Human CD52 (Alemtuzumab) - Fc Mutedâ„¢
Anti-Human CD52 (Alemtuzumab) - Fc Mutedâ„¢ (LT205-GRP)
Products
Description
Clone Campath-1H is a monoclonal antibody that specifically binds to CD52, a protein present on the surface of mature lymphocytes. However, this protein is not present on the stem cells that generated these lymphocytes. Alemtuzumab is targets and destroys mature lymphocytes containing CD-52, and is used to treat chronic lymphocytic leukemia (CLL) and multiple sclerosis. Anti-Human CD52 (Alemtuzumab) utilizes the same variable regions from the therapeutic antibody Alemtuzumab making it ideal for research projects.
Specifications
| Manufacturer Cat# | LT205 |
|---|---|
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium, calcium or preservatives added. |
| Isotype | IgG1 κ |
| Clone | Campath-1H |
| Target | CD52 |
| Applications | CyTOF®, ELISA, FA, FC, IHC FF, IHC FFPE, WB |
| Antigen | CD52 is primarily expressed on the surface of mature lymphocytes. Additionally, CD52 is present on most lymphoid derived malignancies. However, variable expression on Myeloma cells should be noted. |
| Storage | Functional grade biosimilar antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CD52 |