Anti-Human CD4 (Clone OKT-4) – Purified
Anti-Human CD4 (Clone OKT-4) – Purified (C9210-GRP)
Products
Description
CD4 is a 55 kD single-chain type I transmembrane glycoprotein and a member of the Ig superfamily. It is involved in the recognition of MHC class II molecules. Furthermore, CD4 is the primary receptor for HIV. CD4 initiates the early phase of T-cell activation via its association with the T-cell receptor complex and protein tyrosine kinase, Lck. In addition, CD4 functions as a mediator of direct neuronal damage in infectious and immune-mediated diseases of the central nervous system.
Specifications
| Manufacturer Cat# | C9210 |
|---|---|
| Concentration | 0.5 mg/ml |
| Formulation | This purified antibody is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Isotype | IgG2b κ |
| Clone | OKT-4 |
| Target | CD4 |
| Applications | ELISA, FC, ICC, IF Staining, IHC FF, IP, N, WB |
| Antigen | CD4 is expressed on most thymocytes, a subset of T cells, and monocytes/macrophages, and may be detected in thymus, lymph nodes, tonsils, and spleen, and also in specific regions of the brain, gut, and other non-lymphoid tissues. |
| Storage | This purified antibody is stable when stored at 2-8°C. Do not freeze. |
| Protein | CD4 |