Anti-Human CD3 - Purified <i>in vivo </i>PLATINUMâ„¢ Functional Grade
Anti-Human CD3 - Purified <i>in vivo </i>PLATINUMâ„¢ Functional Grade (C664-GRP)
Products
Description
CD3ε is a 20kDa subunit of the TCR complex and is a transmembrane T-cell surface glycoprotein that belongs to the Ig superfamily. It is one of five polypeptide chains that form the TCR complex by associating with the CD3δ, γ and ζ chains, in addition to the TCR α/β or γ/δ chains. CD3 is involved in TCR signaling, enumeration of immunocompetent T-lymphocytes in peripheral blood, and signal transduction during antigen recognition.
Specifications
| Manufacturer Cat# | C664 |
|---|---|
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Isotype | IgG1 κ |
| Clone | UCHT-1 |
| Target | CD3 |
| Applications | Act, CyTOF®, Depletion, FC, ICC, IF Staining, IHC FF, in vivo, IP, PhenoCycler®, WB |
| Antigen | CD3 is expressed on human peripheral blood lymphocytes, splenic lymphocytes, and the majority of T-CLL and T-ALL cells. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CD3 |