Anti-Human CD28 [Clone 37407]
Anti-Human CD28 [Clone 37407] (C1400-GRP)
Products
Description
CD28 is a 44 kD glycoprotein and a member of the Ig superfamily. In its capacity as a costimulatory receptor, CD28 produces co-stimulatory signals necessary for T cell activation and survival. CD28 is the only B7 receptor constitutively expressed on naive T cells. Without having this CD28/B7 interaction, T cells will fail to respond to their specific antigen when coming in contact with an MHC/antigen complex and thus, are said to be anergic.
Specifications
| Manufacturer Cat# | C1400 |
|---|---|
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Cluster of Differentiation 28 MGC138290 Tp44 37407 CD28 Human Anti-Human CD28 |
| Isotype | IgG1 |
| Clone | 37407 |
| Target | CD28 |
| Antibody Type | Monoclonal |
| Applications | FA, WB |
| Antigen | CD28 is expressed on thymocytes, CD4+, CD8+ peripheral T cells, NK cells. |
| Storage | This R-PE conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | CD28 |