Anti-Human CD194 (CCR4) (Mogamulizumab) - Fc Muted™Anti-Human CD194 (CCR4) (Mogamulizumab) - Fc Muted™
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Anti-Human CD194 (CCR4) (Mogamulizumab) - Fc Muted™

Clone KW-0761 (Mogamulizumab) is a research-grade, afucosylated, humanized monoclonal antibody generated from mouse anti-CCR4 mAb7 that targets human CCR4.1 CC chemokine receptor type 4 (CCR4) is a protein that belongs to the G protein-coupled receptor family and is a receptor for a variety of CC chemokines including MCP-1, MIP-1, RANTES, TARC, and Macrophage-derived chemokine. Chemokines are involved in the development, homeostasis, and function of the immune system and are known to regulate cell trafficking of various types of leukocytes. In a 2018 Phase I clinical trial, Mogamulizumab was found to decrease the number of HTLV-1–infected cells and the levels of inflammatory markers related to HTLV-1–Associated Myelopathy.3
Cat# Size Price Qty Buy
LT1005-1mg 1.0 mg
£1,312.50
LT1005-0.2mg 0.2 mg
£328.13
LT1005-25ug 25 ug
£107.81

Additional Information

Property Value or Rating
Manufacturer Cat# LT1005
Concentration ≥ 5.0 mg/ml
Formulation This recombinant monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (PBS) pH 7.2 - 7.4, 150 mM NaCl with no carrier protein, potassium, calcium or preservatives added.
Manufacturer Leinco Technologies Inc
Isotype IgG1 κ
Clone KW-0761
Applications Depletion, ELISA, FA, FC
Antigen CCR4 is primarily expressed by Th2 and regulatory T cells in addition to expression on leukemic cells in cutaneous T-cell lymphoma (CTCL).
Storage Functional grade biosimilar antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Protein CD194

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