Anti-Human CD16 (Clone 3G8) - Purified In vivo GOLD™ Functional GradeAnti-Human CD16 (Clone 3G8) - Purified In vivo GOLD™ Functional Grade
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Anti-Human CD16 (Clone 3G8) - Purified In vivo GOLD™ Functional Grade

CD16 antibody, 3G8, recognizes human CD16, also known as low-affinity IgG receptor III (FcγRIII). There are two distinct forms of CD16, CD16a (FcγRIIIa) and CD16b (FcγRIIIb). CD16a is a 50-65 kDa heterooligomeric polypeptide-anchored transmembrane protein expressed by NK cells, macrophages, and subsets of monocytes1. CD16b is a 48 kDa monomeric glycosylphosphatidylinositol (GPI)-anchored protein expressed on neutrophils1. Upon binding to the Fc portion of IgG or IgG-antigen complex, both CD16 isoforms induce signaling cascades resulting in multiple functions, including phagocytosis, cytokine release, proliferation, degranulation, and antibody dependent cell-mediated cytotoxicity (ADCC)2.
Cat# Size Price Qty Buy
C2858-100mg 100 mg
£2,156.25
C2858-50mg 50 mg
£1,495.31
C2858-25mg 25 mg
£904.69
C2858-5.0mg 5.0 mg
£332.81
C2858-1.0mg 1.0 mg
£98.44

Additional Information

Property Value or Rating
Manufacturer Cat# C2858
Concentration ≥ 5.0 mg/ml
Formulation This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added.
Manufacturer Leinco Technologies Inc
Isotype IgG1 κ
Clone 3G8
Antibody Type Monoclonal
Applications B, CyTOF®, FC, IHC FF, IP
Antigen CD16 is expressed on NK cells, activated monocytes, macrophages, neutrophils, and placental trophoblasts.
Storage Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.
Protein CD16

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