Anti-Human CD14 - Purified <i>In vivo </i>PLATINUMâ„¢ Functional Grade
Anti-Human CD14 - Purified <i>In vivo </i>PLATINUMâ„¢ Functional Grade (C670-GRP)
Products
Description
CD14 is a 53-55 kD GPI-anchored single chain glycoprotein that plays a role in the clearance of gram-negative pathogens by interacting with other proteins, including TLR-4 and MD-2, to mediate the innate immune response to bacterial lipopolysaccharide (LPS). As a high-affinity receptor for LPS, it is involved in the upregulation of adhesion molecules and cytokine expression in monocytes and neutrophils.
Specifications
| Manufacturer Cat# | C670 |
|---|---|
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Isotype | IgG2a |
| Clone | UCHM-1 |
| Applications | FC, WB |
| Antigen | CD14 is expressed on monocytes, macrophages, dendritic cells, and granulocytes. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | CD14 |