Anti-Human CD119 (IFN-γ Rα Chain) - Purified <i>in vivo </i>PLATINUM™ Functional Grade
Anti-Human CD119 (IFN-γ Rα Chain) - Purified <i>in vivo </i>PLATINUM™ Functional Grade (G737-GRP)
Products
Description
IFNγ Rα, or IFNγ R1, is a 90-100 kD type I transmembrane protein that is structurally related to IL-10 receptor. IFNγ Receptor consists of α and ß chains and requires association of JAK1, JAK2 and Stat1 for IFN-γ signal transduction which induces tyrosine phosphorylation of IFN-γ Rα leading to the formation of a docking site on the activated receptor for Stat1, which specifically activates IFN-γ induced gene transcription.
Specifications
| Manufacturer Cat# | G737 |
|---|---|
| Concentration | ≥ 5.0 mg/ml |
| Formulation | This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 - 7.4 with no carrier protein, potassium, calcium or preservatives added. |
| Isotype | IgG1 |
| Clone | GIR-208 |
| Target | IFNγ Rα |
| Antibody Type | Monoclonal |
| Applications | FA, FC, in vivo |
| Antigen | The IFN-γ receptor is expressed at moderate levels on virtually every cell with the exception of erythrocytes. |
| Storage | Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles. |
| Protein | IFNγ Rα |