Anti-Human CCL28 (Clone 62705)
Anti-Human CCL28 (Clone 62705) (C1451-GRP)
Products
Description
CCL28, also known as mucosae-associated epithelial chemokine (MEC), CCK1 and SCYA28, is a chemokine. CCL28 regulates the chemotaxis of cells that express the chemokine receptors CCR3 and CCR10. CCL28 is expressed by columnar epithelial cells in the gut, lung, breast and the salivary glands and drives the mucosal homing of T and B lymphocytes that express CCR10, and the migration of eosinophils expressing CCR3.1,2,3 CCL28 is constitutively expressed in the colon, but its levels can be increased by pro-inflammatory cytokines and certain bacterial products implying a role in effector cell recruitment to sites of epithelial injury.3 CCL28 is a key regulator of IgA antibody-secreting cells (ASCs) accumulation in the mammary gland and thus controls the passive transfer of IgA antibodies from mother to infant.4
Specifications
| Manufacturer Cat# | C1451 |
|---|---|
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody CCL28 SCYA28 MEC CCK1 62705 Human Anti-Human CCL28 |
| Isotype | IgG1 |
| Clone | 62705 |
| Target | CCL28 |
| Antibody Type | Monoclonal |
| Applications | N, WB |
| Storage | This antibody is stable when stored at 2-8°C. Do not freeze. |
| Protein | CCL28 |