Anti-Human Caspase-3 - DyLight® 550
Anti-Human Caspase-3 - DyLight® 550 (C1769-GRP)
Products
Description
Caspase-3 is a member of the caspase family of cysteine proteases and plays a key role in mediating Fas (CD95) and tumor necrosis factor–1 (TNFR-1) induced apoptosis. Caspases can be divided into three groups: apoptotic initiators, apoptotic executioners, and inflammatory mediators.1,2 Caspase-3 is activated during apoptotic signaling events by upstream proteases including caspase 6 and caspase 8.3 Caspase-3 is thought to be essential for chromatin margination, DNA fragmentation and nuclear collapse during apoptosis.3
Specifications
| Manufacturer Cat# | C1769 |
|---|---|
| Concentration | 0.2 mg/ml |
| Formulation | This DyLight® 550 conjugate is formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.4, 1% BSA and 0.09% sodium azide as a preservative. |
| Isotype | IgG1 |
| Clone | C31.129 |
| Target | Caspase-3 |
| Antibody Type | Monoclonal |
| Applications | FC |
| Storage | This DyLight® 550 conjugate is stable when stored at 2-8°C. Do not freeze. |
| Protein | Caspase-3 |