Anti-Human Cardiotrophin-1 (Clone 89215)
Anti-Human Cardiotrophin-1 (Clone 89215) (C1388-GRP)
Products
Description
Human CT-1 is a member of the IL-6 family of cytokines which also includes LIF, CNTF, OSM (Oncostatin M), IL-11, IL-6 and possibly NT-1/ BSF-3. CT-1 is a pleiotropic cytokine which signals through the LIF receptor and the gp130 receptor subunit. CT-1 has the ability to induce cardiac myocyte hypertrophy, and enhances the survival of cardiomyocyte and different neuronal populations. Biologically active human CT-1 is synthesized as a 201 amino acid polypeptide lacking a hydrophobic N-terminal secretion signal sequence. Human and mouse CT-1 share 80% aa sequence identity and exhibit cross-species activity.
Specifications
| Manufacturer Cat# | C1388 |
|---|---|
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Cardiotrophin-1 CTF1 89215 CT-1 Human Anti-Human Cardiotrophin-1 |
| Isotype | IgG1 |
| Clone | 89215 |
| Target | Cardiotrophin-1 |
| Antibody Type | Monoclonal |
| Applications | N, WB |
| Storage | -20°C to -70°C |
| Protein | Cardiotrophin-1 |