Anti-Human BMP-6 (Clone 74219)
Anti-Human BMP-6 (Clone 74219) (B581-GRP)
Products
Description
Bone morphogenetic protein 6, also known as BMP6, is a human gene. The protein encoded by this gene is a a member of the TGFβ superfamily. Bone morphogenetic proteins are known for their ability to induce the growth of bone and cartilage. BMP6 is able to induce all osteogenic markers in mesenchymal stem cells. The bone morphogenetic proteins (BMPs) are a family of secreted signaling molecules that can induce ectopic bone growth. Many BMPs are part of the transforming growth factor-beta (TGFB) superfamily. BMPs were originally identified by an ability of demineralized bone extract to induce endochondral osteogenesis in vivo in an extraskeletal site. Based on its expression early in embryogenesis, the BMP encoded by this gene has a proposed role in early development. In addition, the fact that this BMP is closely related to BMP5 and BMP7 has led to speculation of possible bone inductive activity.
Specifications
| Manufacturer Cat# | B581 |
|---|---|
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody Bone Morphogenetic Protein 6 VGR VGR1 74219 BMP-6 Human Anti-Human BMP-6 |
| Isotype | IgG2b |
| Clone | 74219 |
| Target | BMP-6 |
| Antibody Type | Monoclonal |
| Applications | ELISA Cap, N, WB |
| Storage | -20°C to -70°C |
| Protein | BMP-6 |