Anti-Human B7-H2 (Clone 136726)
Anti-Human B7-H2 (Clone 136726) (B569-GRP)
Products
Description
Human B7-H2, also called B7RP-1, B7h, LICOS, and GL50, is a member of the growing B7 family of immune costimulatory proteins. Other family members include B7-1, B7-2, B7-H1 (PD-L1), PD-L2, and B7-H3. B7 proteins are members of the immunoglobulin (Ig) superfamily, the extracellular domains contain 2 Ig-like domains and all members have short cytoplasmic domains. Among the family members, they share about 20 - 25% amino acid identity. Human and mouse B7-H2 share approximately 49% amino acid identity. B7-H2 has been identified as the ligand for ICOS, a member of the CD28 family of costimulatory receptors. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.
Specifications
| Manufacturer Cat# | B569 |
|---|---|
| Formulation | This monoclonal antibody has been 0.2 µm filtered and lyophilized from modified Dulbecco's phosphate buffered saline (1X PBS) pH 7.2 - 7.3 containing 5.0% w/v trehalose with no calcium, magnesium or preservatives present. |
| Alternate Names | Monoclonal Antibody B7-Homology 2 B7RP-1 B7h LICOS GL50 136726 B7-H2 Human Anti-Human B7-H2 |
| Isotype | IgG2b |
| Clone | 136726 |
| Target | B7-H2 |
| Antibody Type | Monoclonal |
| Applications | CyTOF®, FC, N |
| Storage | -20°C to -70°C |
| Protein | B7-H2 |