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Anti-Human β-Amyloid Precursor Protein (AβNT) (APP)

£107.81

Anti-Human β-Amyloid Precursor Protein (AβNT) (APP) (A162-20ug)

Product

Cat #  A162-20ug Size  20 µg Price 
£107.81
Qty 

Description

Accumulation of the amyloid-β peptide (αβ) in the cerebral cortex is a critical event in the pathogenesis of Alzheimer's disease. The b-amyloid protein precursor (APP) is cleaved by β-secretase, producing a soluble derivative of the protein and a membrane anchored 99-amino acid carboxy-terminal fragment (C99). The C99 fragment serves as substrate for g-secretase to generate the 4 kDa amyloid-b peptide (αβ), which is deposited in the brains of all suffers of Alzheimer's disease.

Specifications

Manufacturer Leinco Technologies Inc
Manufacturer Cat# A162
Product Size 20 µg
Concentration 0.5 mg/ml
Formulation This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative.
Target β-Amyloid Precursor Protein
Applications IHC FFPE, WB
Storage This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Protein β-Amyloid Precursor Protein