Anti-Human Apoptosis Repressor with CARD Domain (NT) (ARC)
£89.06
Anti-Human Apoptosis Repressor with CARD Domain (NT) (ARC) (A160-20ug)
Product
| Cat # A160-20ug | Size 20 µg |
Price
£89.06
|
Qty
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Description
Apoptosis is regulated by death domain (DD) and/or caspase recruitment domain (CARD) containing molecules and a caspase family of proteases. CARD containing cell death regulators include RAIDD, RICK BCL10, Apaf-1, caspase-9, and caspase-2. A novel CARD domain containing protein was recently identified and designated ARC for apoptosis repressor with CARD.1 ARC interacts with caspase-2 and –8 and inhibits enzymatic activity of caspase-8. ARC suppresses apoptosis induced by cell death adapters FADD and TRADD and by cell death receptors Fas, TNFR-1, and DR3. The messenger RNA of ARC is primarily expressed in skeletal muscle and cardiac tissue.1
Specifications
| Manufacturer Cat# | A160 |
|---|---|
| Product Size | 20 µg |
| Concentration | 0.5 mg/ml |
| Formulation | This polyclonal antibody is formulated in phosphate buffered saline (PBS) pH 7.4 containing 0.02% sodium azide as a preservative. |
| Target | Apoptosis Repressor with CARD Domain |
| Applications | WB |
| Storage | This polyclonal antibody is stable for at least one week when stored at 2-8°C. For long term storage, aliquot in working volumes without diluting and store at –20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. |
| Protein | Apoptosis Repressor with CARD Domain |